The world famous spa town of Piešťany is situated in the northern part of the region of Dolné Považie and its fame is associated with the medicinal geothermal water and medicinal sulphuric mud.  It is the largest and most successful Slovak spa specializing in the therapy of diseases of locomotion apparatus. Hot mineral springs (67°-69°C) with the content of 1,500 mg of mineral substances per liter and sulphuric medicinal mud have stimulated the development of spa industry and building of therapeutic facilities.
The park of the Kúpeľný ostrov (the Spa Island) with its fountains and statues offers interesting scenery. Parts of the area include an open-air thermal swimming pool, a network of spa hotels, health care facilities and sport facilities.